I've put a lot of time into learning to read and use topo maps and aerial photos to my advantage. They can definitely save you a lot of time and miles. I walked more or less every inch of the wildlife area that i live next to and noted where i saw most deer sign. After a lot of research and learning what to look for on maps then looking over the maps and finding the saddles on steep ridges, points, ridge line intersections, benches. most of the sign I saw with my own eyes using boots on the ground did match up to where I would have picked to scout using the maps. Some places and terrain features are just too subtle to show up on the maps, though. The only way you will find those is with boots on the ground. Learning to identify small benches using a topo is probably the best thing i've picked up from it. Those benches and the 1/3 down from the top elevation on the leeward side of a ridge seemed to be where I found by far the most buck sign.
Take all that with a grain of salt, though. I just started learning this stuff this year, I've never killed a buck and the season isn't here yet. So, I haven't been able to put it to the test yet.